Obama Team Outlines Four Corporate Donor Packages for Inauguration





WASHINGTON — President Obama’s finance team is offering corporations and other institutions that contribute $1 million exclusive access to an array of inaugural festivities, including tickets to a “benefactors reception,” a children’s concert, a candlelight celebration at the National Building Museum, two reserved parade bleacher seats and four tickets to the president’s official inaugural ball.




The offerings are detailed in an online inaugural fund-raising solicitation provided to The New York Times by an Obama fund-raiser; the document describes four packages that Mr. Obama’s finance team can sell, with differing levels of access depending on the level of contribution. Individuals who contribute $250,000 will receive the same package as million-dollar “institutional donors,” which could include corporations, philanthropies, foundations and unions.


The financing arrangements are a departure from Mr. Obama’s policy in 2009, when he refused corporate donations altogether and capped individual contributions at $50,000. As in 2009, Mr. Obama will not be accepting money from lobbyists or political action committees.


While taxpayers pay for inaugural events at the Capitol — the swearing-in ceremony and inaugural luncheon — the president must raise money from private donors for everything else, including the inaugural parade, ball and concerts. In 2009, Mr. Obama raised $53 million.


The online solicitation, sent to donors by e-mail on Friday, described the different inaugural packages, each named for a former president: Washington ($1 million from institutions and $250,000 from individuals); Adams ($500,000 from institutions and $150,000 from individuals); Jefferson ($250,000 from institutions and $75,000 from individuals); and Madison ($100,000 from institutions and $10,000 from individuals).


Financing arrangements like these are typical for presidential inaugurals; to help pay for President George W. Bush’s 2005 inaugural, dozens of companies, including Home Depot and Bank of America, contributed $250,000 apiece.


But Mr. Obama’s decision has drawn sharp criticism from good-government advocates, who accuse him of abandoning his pledge to keep big money out of politics.


John Wonderlich, policy director of the Sunlight Foundation, which advocates for openness in government, wrote on the group’s blog that the decision “prioritizes a lavish celebration over the integrity of the office,” and that Mr. Obama was “turning away from a principled approach to money in politics.”


The president’s inaugural planners, however, have defended the decision, saying that museums, philanthropic organizations and service groups, like the Red Cross, all accept corporate money. And with Democratic donors feeling tapped out from an expensive presidential campaign, the planners concluded they needed to expand their fund-raising methods.


The 2013 inaugural festivities will be smaller in scope than the huge celebration of 2009, which drew an estimated 1.8 million people to the capital. This time, there will be only three official inaugural balls, as compared with 10 in 2009.


And because Jan. 20, the constitutionally mandated date for the presidential swearing-in, falls on a Sunday this year, Mr. Obama will take his oath in private at the White House, and the public swearing-in ceremony and other events will be held on Monday, Jan. 21.


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Exclusive: Google to replace M&A chief


SAN FRANCISCO (Reuters) - Google Inc is replacing the head of its in-house mergers and acquisitions group, David Lawee, with one of its top lawyers, according to a person familiar with the matter.


Don Harrison, a high-ranking lawyer at Google, will replace Lawee as head of the Internet search company's corporate development group, which oversees mergers and acquisitions, said the source, who spoke anonymously because he was not authorized to speak publicly.


Google is also planning to create a new late-stage investment group that Lawee will oversee, the source said.


Google declined to comment. Lawee and Harrison could not immediately be reached for comment.


One of the Internet industry's most prolific acquirers, Google has struck more than 160 deals to acquire companies and assets since 2010, according to regulatory filings. Many of Google's most popular products, including its online maps and Android mobile software, were created by companies or are based on technology that Google acquired.


Harrison, Google's deputy general counsel, will head up the M&A group at a time when the company is still in the process of integrating its largest acquisition, the $12.5 billion purchase of smartphone maker Motorola Mobility, which closed in May.


And he takes over at a time when the Internet search giant faces heightened regulatory scrutiny, with the U.S. Federal Trade Commission and the European Commission conducting antitrust investigations into Google's business practices. Several recent Google acquisitions have undergone months of regulatory review before receiving approval.


As deputy general counsel, Harrison has been deeply involved in the company's regulatory issues and many of its acquisitions. He joined Google more than five years ago and has completed more than 70 deals at the company, according to biographical information on the Google Ventures website.


Harrison is an adviser to Google Ventures, the company's nearly four-year old venture division which provides funding for start-up companies.


While most of Google's acquisitions are small and mid-sized deals that do not meet the threshold for disclosure of financial terms, Google has a massive war chest of $45.7 billion in cash and marketable securities to fund acquisitions.


Lawee, who took over the M&A group in 2008, has had hits and misses during his tenure. Google shut down social media company Slide one year after acquiring it for $179 million, for example.


The planned late-stage investment group has not been finalized, the source said. The fund might operate separately from Google Ventures, according to the source.


"Think of it as a private equity fund inside of Google," the source said.


The company recently said it would increase the cash it allocates to Google Ventures to $300 million a year, up from $200 million, potentially helping it invest in later-stage financing rounds.


Google finished Friday's regular trading session down 1 percent, or $6.92, at $684.21.


(Reporting By Alexei Oreskovic; editing by Carol Bishopric and Jim Loney)



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Rolling Stones hit NY for 50th anniversary gig


NEW YORK (AP) — "Time Waits for No One," the Rolling Stones sang in 1974, but lately it's seemed like that grizzled quartet does indeed have some sort of exemption from the ravages of time.


At an average age of 68-plus years, the British rockers are clearly in fighting form, sounding tight, focused and truly ready for the spotlight at a rapturously received pair of London concerts last month.


On Saturday, Mick Jagger, Keith Richards, Ronnie Wood and Charlie Watts hit New York for the first of three U.S. shows on their "50 and Counting" mini-tour, marking a mind-boggling half-century since the band first began playing its unique brand of blues-tinged rock.


And the three shows — Saturday's at the new Barclays Center in Brooklyn, then two in Newark, N.J., on Dec. 13 and 15 — aren't the only big dates on the agenda. Next week the Stones join a veritable who's who of British rock royalty and U.S. superstars at the blockbuster 12-12-12 Sandy benefit concert at Madison Square Garden. Also scheduled to perform: Paul McCartney, the Who, Eric Clapton, Bruce Springsteen & The E Street Band, Alicia Keys, Kanye West, Eddie Vedder, Billy Joel, Roger Waters and Chris Martin.


The Stones' three U.S. shows promise to have their own special guests, too. Mary J. Blige will be at the Brooklyn gig, as well as guitarist Gary Clark Jr., the band has announced. (Blige performed a searing "Gimme Shelter" with frontman Jagger in London.) Rumors are swirling of huge names at the Dec. 15 show, which also will be on pay-per-view.


In a flurry of anniversary activity, the band also released a hits compilation last month with two new songs, "Doom and Gloom" and "One More Shot," and HBO premiered a new documentary on their formative years, "Crossfire Hurricane."


The Stones formed in London in 1962 to play Chicago blues, led at the time by the late Brian Jones and pianist Ian Stewart, along with Jagger and Richards, who'd met on a train platform a year earlier. Bassist Bill Wyman and drummer Charlie Watts were quick additions.


Wyman, who left the band in 1992, was a guest at the London shows last month, as was Mick Taylor, the celebrated former Stones guitarist who left in 1974 — to be replaced by Wood, the newest Stone and the youngster at 65.


The inevitable questions have been swirling about the next step for the Stones: another huge global tour, on the scale of their last one, "A Bigger Bang," which earned more than $550 million between 2005 and 2007? Something a bit smaller? Or is this mini-tour, in the words of their new song, really "One Last Shot"?


The Stones won't say. But in an interview last month, they made clear they felt the 50th anniversary was something to be marked.


"I thought it would be kind of churlish not to do something," Jagger told The Associated Press. "Otherwise, the BBC would have done a rather dull film about the Rolling Stones."


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Associated Press writer David Bauder contributed to this report.


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Job Growth Is Steady Despite Storm and Fiscal Impasse




A Lower Than Expected Jobless Rate:
The U.S. Labor Department reports a sharper increase in job creation than economists had been expecting.







Shaking off the effects of Hurricane Sandy and the looming fiscal impasse in Washington, the economy created 146,000 jobs in November, well above the level economists had been expecting.






Source: Bureau of Labor Statistics





The report released Friday by the Labor Department also showed the unemployment rate fell to 7.7 percent, the lowest level in four years. But the drop came largely from a decline in the number of people seeking work and counted as officially unemployed.


Among specific industries, the retail sector was especially healthy, adding 53,000 jobs as the holiday shopping season approached. In the last three months, retail employment has increased by 140,000.


One notable point of weakness was the manufacturing sector, which lost 7,000 jobs in the month. Demand from Europe and other overseas markets has weakened recently, while some manufacturing companies have held off on spending as political leaders square off in Washington over how to cut the deficit.


Highlighting just how vulnerable to shocks the economy remains, one widely followed index of consumer sentiment showed a marked drop in early December. The Thomson Reuters/University of Michigan’s index of consumer confidence, released Friday, fell to 74.5, down from 82.7 in November.


That was the lowest it has been since August – a decline that Bricklin Dwyer, an economist with BNP Paribas, attributed to the showdown in Washington over the budget.


“The deterioration in consumers’ future expectations was probably related to increased concerns relating to the political theater surrounding the ‘fiscal cliff’ negotiations,” he wrote in a report Friday.


The Labor Department revised job growth in previous months downward somewhat. October growth fell to 138,000 from an initial estimate 171,000, and September’s declined to 132,000 from 148,000. Average hourly earnings in November rose 0.2 percent, the report showed.


By the widest measure of joblessness, unemployment also eased slightly: after factoring in people looking for work as well as those forced to take part-time positions because full-time work wasn’t available, the total unemployed fell to 14.4 percent in November from 14.6 percent in October.


The report for November was relatively strong, economists said, and showed fewer effects from Hurricane Sandy that had been expected. In Friday’s announcement, the Bureau of Labor Statistics said the storm did “not substantively impact the national employment and unemployment estimates for November.”


Ethan Harris, co-head of global economics at Bank of America of Merrill Lynch, said, “It’s a pretty solid report. It’s consistent with a slow recovery in the job market.”


“It’s encouraging that with the fiscal cliff looming, the corporate sector seems willing to hire even with the worries about what’s going in Washington,” Mr. Harris said.


If the budget impasse can’t be resolved this month, however, it’s likely that jobs growth will weaken early next year, he added. “The fiscal cliff is a very dangerous game,” he said.


Indeed, other economists remained cautious about the jobs outlook.


“It’s not something to get too excited about,” said Nigel Gault, chief United States economist for IHS Global Insight. “The number is 146,000 and the average so far this year is 151,000. We’re pretty much in line with what we’ve been doing.”


Mr. Gault said Hurricane Sandy’s impact may have been seen in construction, where the number of jobs fell by 20,000, as well as in manufacturing.


The labor participation rate, which represents the proportion of the adult population that is either employed or actively looking for work, remains very low by historical standards.


At 63.6 percent in November, Mr. Gault said, it was just 0.1 percent above the low point for the current economic cycle, which was reached in August 2012.


“We’re not at the point in which the jobs market is strong enough to pull discouraged workers back into the labor market," he said.


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Italian tax police visit Facebook's Milan offices


MILAN (Reuters) - Italian police have been carrying out checks at the Milan offices of Facebook to assess whether it regularly declared its income in Italy, an investigative source and the U.S. company said on Friday.


Italian officials have stepped up their efforts to collect taxes in recent months and have already targeted other big corporate names such as Google to check whether they are paying their dues.


The investigative source said tax officials first went to the offices of Facebook in Milan nearly a month ago to collect documents.


"Facebook pays taxes in Italy as part of its business activity in the country and strictly complies with Italy's fiscal rules," Facebook said in an emailed statement.


"Facebook has fully cooperated with tax police during the investigation and intends to continue to do that."


Italian police opened a new tax probe into Google Italy last week, five years after an earlier investigation into transfer pricing.


Google has said it complies with the tax laws in every country in which it operates.


($1=0.7700 euros)


(Reporting by Emilio Parodi and Claudia Cristoferi, Writing by Antonella Ciancio; Editing by Greg Mahlich)



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Hospital: Nurse involved in Kate hoax call dies


LONDON (AP) — A nurse who fell victim to a prank telephone call seeking information about the pregnant Duchess of Cambridge has died, the London hospital where she worked reported Friday.


The King Edward VII hospital said nurse Jacintha Saldanha took the hoax call by two Australian radio disc jockeys who impersonated Queen Elizabeth II and Prince Charles early Tuesday to elicit private information on the duchess's condition. Saldanha later transferred the call to the nurse caring for the duchess, who is suffering from acute morning sickness. That second nurse spoke freely about her 30-year-old patient, one of the world's most photographed women.


Saldanha was found dead early Friday. Police say her death is unexplained.


"Our thoughts and deepest sympathies at this time are with her family and friends," said John Lofthouse, the hospital's chief executive, said in a statement. "Everyone is shocked by the loss of a much-loved and valued colleague."


St. James's Palace, which speaks for Prince William, the duchess' husband, also expressed sadness about the nurse's death, but insisted that it had not complained about the hoax.


"On the contrary, we offered our full and heartfelt support to the nurses involved and hospital staff at all times," the palace said in a statement.


The prank phone call took place early Tuesday and the two radio personalities apologized the following day.


A woman using the often-mimicked voice of Britain's monarch asked after the duchess' health. She was told by the second nurse who took the call from Saldanha that the duchess, the former Kate Middleton, "hasn't had any retching with me and she's been sleeping on and off."


The nurse went on to say the duchess had had an uneventful night, as another radio employee pretended to be a dog yapping in the background. The alleged queen and prince then talked about traveling to the London hospital to check in on the patient, who is married to the queen's grandson, Prince William.


The hospital said it supported Saldanha in the aftermath of the call and that its phone protocols were under review.


The Australian station 2DayFM placed the recording of the conversation on its website but later said it was sorry. Australian radio personalities Mel Greig and Michael Christian apologized for the hoax.


"We were very surprised that our call was put through. We thought we'd be hung up on as soon as they heard our terrible accents," they said in a joint statement with the station at the time. "We're very sorry if we've caused any issues and we're glad to hear that Kate is doing well."


However, the disc jockeys also described the call as the "easiest prank call ever made," and promoted it through the station's website and social media accounts.


The Sydney-based 2Day FM continued promote its prank call on air early Saturday morning. It described the hoax as "the prank call the world is talking about" before playing clips of news programs reporting on the original call.


Christian's Twitter account has since been taken down.


Officials from St. James's Palace have said the duchess is not yet 12 weeks pregnant. The child would be the first for her and Prince William and become third in line to the British throne, after Charles and William.


___


Associated Press Writers Paisley Dodds and Cassandra Vinograd contributed to this story.


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Resignations Continue in Egypt as Tanks Deploy Around Presidential Palace





CAIRO — Resignations rocked the government of President Mohamed Morsi on Thursday as tanks from the special presidential guard took up positions around his palace and the state television headquarters after a night of street fighting between his Islamist supporters and their secular opponents that left at least 6 dead and 450 wounded.




The director of state broadcasting resigned Thursday, as did Rafik Habib, a Christian who was the vice president of the Muslim Brotherhood’s Freedom and Justice Party and the party’s favorite example of its commitment to tolerance and pluralism. Their departures followed an announcement by Zaghoul el-Balshi, the new general secretary of the commission overseeing a planned constitutional referendum, that he was quitting. “I will not participate in a referendum that spilled Egyptian blood,” he said in a television interview during the clashes late Wednesday night.


With the resignations on Thursday, nine Morsi administration officials have quit in protest in recent days. In a day of tension and uncertainty unlike any other since the revolt that overthrew Hosni Mubarak nearly two years ago, state media reported that Mr. Morsi, of the Muslim Brotherhood’s political arm, was meeting with his top advisers and would deliver a public address in response to the clashes. The top scholar of Al Azhar, the center of Sunni Muslim learning that is considered Egypt’s chief moral authority, urged both sides to pull back from violence and seek “rational dialogue.”


The scale of the violence around the palace has raised the first doubts about Mr. Morsi’s effort to hold a public referendum on Dec. 15 to vote on a draft constitution approved by his Islamist allies over the objections of his secular opposition and the Coptic Christian Church.


About 1 p.m. Thursday, hundreds of his supporters who had camped outside his palace to defend it — many waking up with bandaged heads from wounds sustained from volleys of rocks and the blows of makeshift clubs the previous night — abruptly began to pull out of their encampment in unison, a development that suggested that their organizers in the Muslim Brotherhood had ordered a withdrawal. It took place just moments after several Brotherhood members camped there had vowed to stay put until the referendum, set for Dec. 15.


The Egyptian military, which seized power from Mr. Mubarak in February 2011, saying it was stepping in to protect the legitimate demands of the public, stayed silent after a statement Wednesday that it would not intervene in a dispute between political factions. The presidential guard that deployed Thursday is a separate unit that reports directly to the president.


Wednesday night’s battle was the worst clash between political factions here since the days of President Gamal Abdel Nasser’s military coup six decades ago, and Egyptians across the political spectrum responded with shock and dismay.


Abdel Moneim Aboul Fotouh, a popular former leader of the Muslim Brotherhood who ran for president as a liberal Islamist and has stayed on the sidelines of the escalating conflict between Mr. Morsi and his secular opponents, slammed the president and the Brotherhood for calling on their civilian supporters to defend the palace with force rather than relying the institutions of law enforcement.


“The palace is not a private property to the Muslim Brotherhood or Dr. Morsi; it belongs to us, all Egyptians,” Mr. Aboul Fotouh said in a televised news conference. He was flanked by a Morsi adviser who had just resigned and by a well-known revolutionary poet who is the son of Sheik Yusuf al-Qaradawi, perhaps the most influential religious scholar in the Sunni Muslim world and a spiritual guru to the Muslim Brotherhood.


Wednesday night’s clashes followed two weeks of sporadic violence around the country that erupted after Mr. Morsi, a former leader of the Muslim Brotherhood movement, seized temporary powers beyond the review of any court, removing the last check on his authority until ratification of the new constitution.


Mr. Morsi has said he needed the expanded powers to block a conspiracy by corrupt businessmen, Mubarak-appointed judges and opposition leaders to thwart Egypt’s transition to a constitutional democracy. Some opponents, Mr. Morsi’s advisers say, would sacrifice democracy to stop the Islamists from winning elections.


Mr. Morsi’s secular critics have accused Mr. Morsi and the Islamists of seeking to establish a new dictatorship, in part by ramming through a rushed constitution that they say could ultimately give new power over society to Muslim scholars and Islamists groups. And each side’s actions have confirmed the other’s fears.


Mai Ayyad contributed reporting.



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Apple's market cap falls below $500 billion as shares keep falling


NEW YORK (Reuters) - Apple's market capitalization fell below $500 billion on Thursday as shares of the world's most valuable listed company continued to slide after suffering their worst one-day decline in nearly four years.


Shares of Apple Inc fell to as low as $518.63 on Thursday, declining nearly 10 percent for the week. But for the year, the stock is still up more than 30 percent. At its peak in September the stock was worth $705.07.


Earlier in the day, research firm IDC said Apple's rank in China's smartphone market, which is set to become the world's largest this year, fell to No.6 in the third quarter as it faced tough competition from Chinese brands.


IDC's announcement comes a day after Apple's shares fell more than 6 percent on the Nasdaq, logging its biggest single-day loss in four years and losing $35 billion of its value, on concerns about rivals gaining ground in the mobile devices market.


(Reporting by Angela Moon and Rodrigo Campos; Editing by James Dalgleish)



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Individuality takes center stage at Grammys


Fun. helped break up the sound of dance and electronic music on Top 40 radio with its edgy pop-rock grooves. Frank Ocean made a bold statement in R&B — with an announcement about his sexuality and with his critically revered, multi-genre album, "channel ORANGE." And Mumford & Sons continued to bring its folk-rock swag and style to the Billboard charts with its sophomore album.


They all were rewarded Wednesday when The Recording Academy announced the nominees for the 2013 Grammy Awards.


Those acts, who scored the most nominations with six each, were joined by typical Grammy contenders like Jay-Z and Kanye West, who also got six nominations. The Black Keys' drummer, Dan Auerbach, is also up for six awards, thanks to his nomination for producer of the year. His band earned five nods, along with R&B singer Miguel and jazz pianist Chick Corea.


"It feels like alternative music is back," said fun. guitarist Jack Antonoff. His band's gold-selling "Some Nights" is up for album of the year, competing with Black Keys' "El Camino," Mumford & Sons' "Babel," Jack White's "Blunderbuss" and "channel ORANGE," the major label debut from Ocean.


Fun. is nominated in all of the major categories, including best new artist, and record and song of the year for its breakthrough anthem "We Are Young."


Ocean, whose mother attended the nominations special, scored nods in three of the top four categories. His song "Thinkin Bout You" — which he originally wrote for another singer — will compete for record of the year with Black Keys' "Lonely Boy" and four No. 1 hits: Taylor Swift's "We Are Never Ever Getting Back Together," ''Somebody I Used to Know" by Gotye and Kimbra, Kelly Clarkson's "Stronger (What Doesn't Kill You)" and "We Are Young" by fun.


Song of the year, too, features some No. 1 hits, including fun. and Clarkson's jams, as well as Carly Rae Jepsen's viral smash "Call Me Maybe." But then there's Ed Sheeran's "The A Team," a slow groove about a homeless prostitute, and Miguel's "Adorn," the R&B singer-songwriter's crossover hit.


"It's like one of those songs that wrote itself and I was the vessel," the 26-year-old said in an phone interview from New York City late Wednesday, where he performed with Trey Songz and Elle Varner.


While Miguel's excited to compete for song of the year, he's more thrilled about his sophomore album's nomination for best urban contemporary album, a new category that recognizes R&B albums with edge and multiple sounds.


"That's a huge complement to say that your entire body of work was the best of the year," he said of "Kaleidoscope Dream." ''That's the one that means the most to me. I'm really hoping maybe, just maybe."


Miguel, along with Gotye, Alabama Shakes and the Lumineers, is part of the pack of nominees who have showcased individuality and have marched to the beat of their own drum in today's music industry.


Though nominated albums by The Black Keys and Mumford & Sons are platinum-sellers, their songs are not regularly heard on Top 40 radio. Electronic and dance music, which has dominated radio airplay for a few years, were left out of the top awards this year. Also, One Direction — the boy band that released two top-selling albums this years and sold-out many arenas — was snubbed for best new artist.


Lionel Richie has one of the year's top-selling albums with his country collaboration collection, "Tuskegee," but he didn't earn any nominations. And Nicki Minaj, who released a gold-selling album this year and had a hit with "Starships," wasn't nominated for a single award.


Jay-Z and West dominated the rap categories, a familiar refrain at the Grammys. Nas scored four nominations, including best rap album for "Life Is Good." Jeff Bhasker, the producer behind fun.'s breakthrough album, also scored four nods.


Swift, who released her latest album, "Red," after the Grammy eligibility date, still scored three nominations, including two for "Safe & Sound" with The Civil Wars. Country acts were mainly left out of the major categories this year, though the genre usually has success at the Grammys. Aside from Swift's pop song competing for record of the year, there is 21-year-old Hunter Hayes, who is up for best new artist against fun., Ocean, Alabama Shakes and the Lumineers.


"I'm so proud to be, as you say, representing country music in the new artist category," said Hayes, who is also nominated for best country album and country solo performance. "I don't even feel worthy of saying that, but it's so cool for me to be able to say that."


Swift hosted the CBS special with LL Cool J and it featured performances by The Who and Maroon 5, who received multiple nominations.


The five-year-old nominations show spent its first year outside Los Angeles, making its debut in Nashville, Tenn., at the Bridgestone Arena. It marked the largest venue the show has been held in.


The 55th annual Grammy Awards take place Feb. 10 in Los Angeles.


___


Online:


http://www.grammys.com


___


AP Music Writer Chris Talbott and AP Writer Caitlin R. King in Nashville contributed to this report.


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Extended Use of Breast Cancer Drug Suggested


The widely prescribed drug tamoxifen already plays a major role in reducing the risk of death from breast cancer. But a new study suggests that women should be taking the drug for twice as long as is now customary, a finding that could upend the standard that has been in place for about 15 years.


In the study, patients who continued taking tamoxifen for 10 years were less likely to have the cancer come back or to die from the disease than women who took the drug for only five years, the current standard of care.


“Certainly, the advice to stop in five years should not stand,” said Prof. Richard Peto, a medical statistician at Oxford University and senior author of the study, which was published in The Lancet on Wednesday and presented at the San Antonio Breast Cancer Symposium.


Breast cancer specialists not involved in the study said the results could have the biggest impact on premenopausal women, who account for a fifth to a quarter of new breast cancer cases. Postmenopausal women tend to take different drugs, but some experts said the results suggest that those drugs might be taken for a longer duration as well.


“We’ve been waiting for this result,” said Dr. Robert W. Carlson, a professor of medicine at Stanford University. “I think it is especially practice-changing in premenopausal women because the results do favor a 10-year regimen.”


Dr. Eric P. Winer, chief of women’s cancers at the Dana-Farber Cancer Institute in Boston, said that even women who completed their five years of tamoxifen months or years ago might consider starting on the drug again.


Tamoxifen blocks the effect of the hormone estrogen, which fuels tumor growth in estrogen receptor-positive cancers that account for about 65 percent of cases in premenopausal women. Some small studies in the 1990s suggested that there was no benefit to using tamoxifen longer than five years, so that has been the standard.


About 227,000 cases of breast cancer are diagnosed each year in the United States, and an estimated 30,000 of them are in premenopausal women with estrogen receptor-positive cancer and prime candidates for tamoxifen. But postmenopausal women also take tamoxifen if they cannot tolerate the alternative drugs, known as aromatase inhibitors.


The new study, known as Atlas, included nearly 7,000 women with ER-positive disease who had completed five years of tamoxifen. They came from about three dozen countries. Half were chosen at random to take the drug another five years, while the others were told to stop.


In the group assigned to take tamoxifen for 10 years, 21.4 percent had a recurrence of breast cancer in the ensuing 10 years, meaning the period 5 to 14 years after their diagnoses. The recurrence rate for those who took only five years of tamoxifen was 25.1 percent.


About 12.2 percent of those in the 10-year treatment group died from breast cancer, compared with 15 percent for those in the control group.


There was virtually no difference in death and recurrence between the two groups during the five years of extra tamoxifen. The difference came in later years, suggesting that tamoxifen has a carry-over effect that lasts long after women stop taking it.


Whether these differences are big enough to cause women to take the drug for twice as long remains to be seen.


“The treatment effect is real, but it’s modest,” said Dr. Paul E. Goss, director of breast cancer research at the Massachusetts General Hospital.


Tamoxifen has side effects, including endometrial cancer, blood clots and hot flashes, which cause many women to stop taking the drug. In the Atlas trial, it appears that roughly 40 percent of the patients assigned to take tamoxifen for the additional five years stopped prematurely.


Some 3.1 percent of those taking the extra five years of tamoxifen got endometrial cancer versus 1.6 percent in the control group. However, only 0.6 percent of those in the longer treatment group died from endometrial cancer or pulmonary blood clots, compared with 0.4 percent in the control group.


“Over all, the benefits of extended tamoxifen seemed to outweigh the risks substantially,” Trevor J. Powles of the Cancer Center London, said in a commentary published by The Lancet.


Dr. Judy E. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, said many women have a love-hate relationship with hormone therapies.


“They don’t feel well on them, but it’s their safety net,” said Dr. Garber, who added that the news would be welcomed by many patients who would like to stay on the drug. “I have patients who agonize about this, people who are coming to the end of their tamoxifen.”


Emily Behrend, who is a few months from finishing her five years on tamoxifen, said she would definitely consider another five years. “If it can keep the cancer away, I’m all for it,” said Ms. Behrend, 39, a single mother in Tomball, Tex. She is taking the antidepressant Effexor to help control the night sweats and hot flashes caused by tamoxifen.


Cost is not considered a huge barrier to taking tamoxifen longer because the drug can be obtained for less than $200 a year.


The results, while answering one question, raise many new ones, including whether even more than 10 years of treatment would be better still.


Perhaps the most important question is what the results mean for postmenopausal women. Even many women who are premenopausal at the time of diagnosis will pass through menopause by the time they finish their first five years of tamoxifen, or will have been pushed into menopause by chemotherapy.


Postmenopausal patients tend to take aromatase inhibitors like anastrozole or letrozole, which are more effective than tamoxifen at preventing breast cancer recurrence, though they do not work for premenopausal women.


Mr. Peto said he thought the results of the Atlas study would “apply to endocrine therapy in general,” meaning that 10 years of an aromatase inhibitor would be better than five years. Other doctors were not so sure.


The Atlas study was paid for by various organizations including the United States Army, the British government and AstraZeneca, which makes the brand-name version of tamoxifen.


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